Morning: Arrive in Santiago, settle into your hotel, and enjoy a leisurely breakfast.
Afternoon: Explore Plaza de Armas and visit the La Moneda Palace, getting acquainted with Chile’s vibrant capital.
Evening: Dinner in the Bellas Artes district and enjoy views from Cerro San Cristóbal at sunset.
Find HotelsMorning: Travel to Valparaíso, famous for its colorful hills and street art.
Afternoon: Visit the Pablo Neruda Museum (La Sebastiana) and stroll through the harbour.
Evening: Head to Viña del Mar for dinner by the beach and a relaxing sunset walk.
Find HotelsMorning: Fly into Lima and check into your hotel.
Afternoon: Explore Plaza Mayor, visit the Lima Cathedral and San Francisco Monastery.
Evening: Sample Peruvian cuisine in the Miraflores district with ocean views.
Find HotelsMorning: Fly or take bus to Cusco; acclimate to altitude with light exploration of Plaza de Armas.
Afternoon: Day tour of the Sacred Valley visiting Pisac Market and Ollantaytambo ruins.
Evening: Enjoy traditional Andean music and cuisine in Cusco’s historic center.
Find HotelsMorning: Early train to Aguas Calientes, then bus to Machu Picchu.
Afternoon: Guided tour of Machu Picchu, exploring the ancient citadel.
Evening: Return to Cusco for rest and dinner.
Find HotelsMorning: Flight or bus to La Paz, Bolivia's high-altitude capital.
Afternoon: Visit Valley of the Moon with its unique lunar landscapes.
Evening: Discover local markets and sample Bolivian street food in Witches’ Market.
Find HotelsMorning: Begin 3-day tour of the Uyuni Salt Flats, the world’s largest salt desert.
Afternoon: Visit Incahuasi Island covered in giant cacti and explore sparkling salt formations.
Evening: Overnight in a salt hotel, stargazing in the clear desert sky.
Find HotelsMorning: Explore colorful lagoons like Laguna Colorada with flamingos.
Afternoon: Visit geothermal fields and hot springs before heading back to La Paz.
Evening: Relax in La Paz with a warming cup of coca tea.
Find HotelsMorning: Fly to Asunción, Paraguay’s capital.
Afternoon: Visit the historic Palacio de los López and National Pantheon of the Heroes.
Evening: Stroll along Costanera de Asunción riverfront and enjoy local cuisine.
Find HotelsMorning: Ferry to Colonia del Sacramento, UNESCO heritage town.
Afternoon: Explore the cobblestone streets and Historic Quarter.
Evening: Enjoy sunset views from the Colonia Lighthouse.
Find HotelsMorning: Bus to Montevideo, explore Plaza Independencia.
Afternoon: Wander the Ciudad Vieja historic district and visit the Mercado del Puerto.
Evening: Experience tango or local music performances.
Find HotelsMorning: Travel to Buenos Aires, settle in.
Afternoon: Visit La Boca neighborhood and Recoleta Cemetery.
Evening: Attend an authentic tango show with dinner.
Find HotelsMorning: Fly or bus to Mendoza, center of Argentina’s wine country.
Afternoon: Day tours visiting Malbec vineyards and wineries.
Evening: Sample regional dishes and local wines.
Find HotelsMorning: Fly to El Calafate, gateway to Patagonia.
Afternoon: Visit Perito Moreno Glacier, walk along the viewing platforms.
Evening: Overnight in El Calafate, relax after a day of hiking.
Morning (Day 27-29): Transfer to Torres del Paine National Park for hiking, wildlife spotting, and exploring dramatic scenery.
Afternoon: Hike to the Towers of Paine and other iconic viewpoints.
Evening: Camp or stay in refugios under Patagonian skies.
Find HotelsMorning: Travel to San Carlos de Bariloche, known for lakes and Swiss-style architecture.
Afternoon: Explore Cerro Catedral or take a boat tour on Lago Nahuel Huapi.
Evening: Enjoy chocolate shops and local cuisine.
Find HotelsMorning: Fly back to Buenos Aires.
Afternoon: Last-minute shopping or museum visit such as MALBA.
Evening: Farewell dinner revelling in Argentine flavors and culture.
Find HotelsTotal Estimated Cost: $2,825
If you want to extend your trip, consider adding more days in Patagonia for extended trekking or wildlife tours, and allow an extra week in Peru to explore the Amazon basin. For a shorter itinerary, focus on highlights: skip Paraguay and Uruguay, concentrate on Chile, Peru, Bolivia, and Argentina main attractions, and reduce time in Patagonia to essential hikes only.