Morning: Depart LAS on United Flight UA 845 (5:45 AM) and land at DEN (9:15 AM). Transfer to your downtown Airbnb, “Cozy Loft Near City Park,” and settle in.
Afternoon: Stroll to Denver Botanic Gardens for a relaxed walk among seasonal displays, then enjoy a light lunch at the nearby Cherry Creek Marketplace food hall.
Evening: Dine at Root Down for farm‑to‑table cuisine, followed by a sunset view from the Red Rocks Amphitheatre (outside concert schedule).
Find HotelsMorning: Take the free RT Light Rail to the Denver Museum of Nature & Science and explore the dinosaur exhibit and space arena.
Afternoon: Hop on the Free MallRide to the historic Union Station, then wander the Lower Downtown (LoDo) district for art galleries and boutique shops.
Evening: Ride the City Bus #15 to the Mount Evans Scenic Byway (partial drive not required; bus tour available) for breathtaking mountain vistas, returning for a nightcap at The Cruise Room.
Find HotelsMorning: Board the Greyhound Express (depart 8:30 AM) from Denver Bus Station to Santa Fe (arrive 2:30 PM). Check into “Adobe Charm Villa” near the Plaza.
Afternoon: After a short rest, explore the Santa Fe Plaza, visiting the Cathedral Basilica of St. Francis of Assisi and local artisan stalls.
Evening: Savor New Mexican cuisine at The Shed, then attend a traditional Navajo storytelling session at the nearby cultural center.
Find HotelsMorning: Walk to the Georgia O’Keeffe Museum and admire iconic Southwestern artworks, followed by a coffee break at Cafe Pasqual’s.
Afternoon: Take the local Santa Fe Trails Bus to the historic San Miguel Mission and then hike the gentle paths of Railyard Park.
Evening: Join a guided Santa Fe Night Walk highlighting Pueblo Revival architecture, ending with dinner at La Boca for Spanish tapas.
Find HotelsMorning: Board the Santa Fe Trails Bus #200 to Bandelier National Monument for a ranger‑led hike among ancient cliff dwellings.
Afternoon: Continue to Los Alamos via the same bus line, visiting the Bradbury Science Museum for a glimpse into Manhattan Project history.
Evening: Return to Santa Fe, relax at the Airbnb’s private patio, and enjoy a starlit dinner prepared with locally sourced ingredients.
Find HotelsMorning: Pack and enjoy a leisurely brunch at Café Pasqual’s, then stroll through the Santa Fe Farmers Market for last‑minute souvenirs.
Afternoon: Take the Greyhound Express (depart 12:30 PM) back to Denver, then catch United Flight UA 846 (3:45 PM) arriving LAS at 5:15 PM, just before the 5:00 PM deadline.
Evening: Arrive home, reflecting on the blend of mountain scenery, indigenous heritage, and artistic culture experienced over the past five nights.
Find HotelsIf you wish to extend the trip, add an extra night in Denver to explore nearby Rocky Mountain National Park via the free ROCKY MOUNTAIN Express bus. To shorten the itinerary, combine Day 4 and Day 5 activities in Santa Fe, skipping the Los Alamos stop, which reduces travel time and overall cost while still delivering a rich cultural experience.