Morning: Depart Tucson on an early‑morning bus, crossing the border at Santa Cruz and enjoying desert scenery.
Afternoon: Arrive in Hermosillo, check into a discounted Airbnb, and take a short walk to the Plaza Zaragoza for a quick lunch.
Evening: Stroll along Malecon de Hermosillo, savor local tacos, and rest for the week ahead.
Book a HotelMorning: Alternate visits to the Hermosillo Cathedral, Casa de la Cultura, and the Museo de Sonora for culture and history.
Afternoon: Relax at Parque Hidalgo, sample street‑food at Mercado Municipal, and enjoy a desert‑landscape bike ride.
Evening: Experience live music at local venues, try regional wine, and unwind at your Airbnb.
Book a HotelMorning: Board a comfortable overnight bus from Hermosillo to Mexico City, crossing into the highlands.
Afternoon: Arrive, drop luggage at a centrally located Airbnb, and have a light lunch at Café de Tacuba.
Evening: Take a brief walk around the historic Zócalo to get a feel for the city’s energy.
Book a HotelMorning: Catch an early flight from Mexico City to Cuenca, Ecuador, arriving by midday.
Afternoon: Transfer to a discounted Airbnb in the historic district, then explore the New Cathedral and nearby plazas.
Evening: Dine at a local restaurant serving cuy and enjoy a sunset view from the Mirador de Turi.
Book a HotelMorning: Rotate between the Panorama Cultural Center, day trips to the Inca ruins of Ingapirca, and coffee‑plantation tours in the surrounding valleys.
Afternoon: Visit artisan markets, take language‑exchange meet‑ups, and unwind at the Rio Tomebamba parks.
Evening: Sample Ecuadorian cuisine, attend live folk music, and relax in your Airbnb with discount‑rate utilities.
Book a HotelMorning: Depart Cuenca on a connecting flight to Montevideo, Uruguay, arriving by early afternoon.
Afternoon: Settle into a long‑term Airbnb (discount applied), then wander the Ciudad Vieja cobblestone streets.
Evening: Enjoy a coastal dinner at the Rambla of Montevideo, watching the sunset over the Río de la Plata.
Book a HotelMorning: Explore the Mercado del Puerto, take a bike ride along the Rambla, and visit museums like the Museo Nacional de Artes Visuales.
Afternoon: Day trips to nearby wine regions (e.g., Canelones), beach time at Punta del Este (optional), and local cooking classes.
Evening: Join tango evenings, sample Uruguayan steak, and enjoy the relaxed nightlife before returning to your Airbnb.
Book a HotelTotal Estimated Cost: $2,585
If you need to shorten the adventure, consider dropping the week in Hermosillo and flying directly from Tucson to Mexico City, then onward to Cuenca. To extend, add a few extra days in Montevideo to explore the nearby coastal towns of Piriápolis and La Paloma, or take a weekend excursion to Colonia del Sacramento. Using the same discounted Airbnb rates and public transport keeps the budget friendly throughout.