After arriving and dropping bags, start your first morning with a leisurely stroll through Old Town Square, watching the hourly show of the Prague Astronomical Clock and sipping a coffee at a nearby café while soaking in the Gothic and Baroque facades. From there walk toward Powder Tower and continue to Municipal House for a quick look inside at its Art Nouveau interiors, then grab a warm trdelník from a street vendor and cross toward the castle area to queue for early entry to St. Vitus Cathedral, setting you up to explore the castle complex in the afternoon.
After exploring the castle complex, wander down to the charming streets of Golden Lane for its tiny historic houses and artisan shops, then cross to the quieter side of the castle hill to visit the peaceful gardens of Vrtba Garden for winter views and photographs. Continue with a leisurely descent toward Kampa Island, where you can stroll along the river, see the modern outdoor sculptures at Kampa Museum (exterior and courtyard), and warm up with a bowl of traditional Czech goulash at a riverside bistro before heading toward Lesser Town for the evening.
As dusk falls, wander down to Charles Bridge for a quieter, lamp-lit crossing and catch the view of the city reflected in the Vltava before turning toward the lively district of Malá Strana. Enjoy a traditional Czech dinner at Lokál U Bílé Kuželky (or a similar local pub) to taste svíčková or roast pork with dumplings, then finish the night with cocktails at the rooftop bar of Hotel U Prince or a cozy concert of Czech chamber music at St. Nicholas Church to cap a full first day.
Start with a peaceful breakfast at Café Savoy to sample a buttery koláč and strong Czech coffee, then stroll through the baroque lanes to the leafy hillside of Petřín Hill, taking the funicular up for panoramic views and a visit to the mirror maze at the Petřín Lookout Tower. Descend toward the riverside to wander the art-lined paths of Kampa Park, stop at a riverside stall for a warm smoked trout or open-faced chlebíček, and cross the quieter pedestrian bridges to reach the ornate St. Nicholas Church (Malá Strana) for a short interior visit before lunch, keeping the day's pace relaxed after yesterday's castle exploration.
Descend from Petřín Hill toward the riverside and head east along the Vltava to explore the leafy promenade at Smetana Embankment, pausing for views of the river and the sculptural ensemble of The Singing Fountain before boarding a short daytime river cruise to see Prague's bridges from the water. After the cruise, wander into the atmospheric lanes of Nerudova Street to browse artisan shops, then warm up with hearty roast beef and dumplings at the historic tavern U Malířů or sample a modern Czech tasting menu at Hergetova Cihelna overlooking the river.
As twilight deepens, wander into the bohemian streets around Riegrovy Sady for a panoramic sunset over the city, then descend to the riverside to explore the atmospheric cafés and galleries of Výtoň and the modern art space DOX Centrum (evening exhibitions and a bar area). Finish with a relaxed meal of smoked trout or modern Czech tapas at the waterfront Mlynec Restaurant followed by live jazz at the intimate Reduta Jazz Club, keeping the night lively but easy after a full day of walking.
Begin your final morning with a visit to Naplavka Farmers' Market (if open) for fresh pastries, local cheeses and a last espresso while watching the river traffic, then stroll upriver to browse contemporary Czech design at the small galleries of Street Gallery Prague. Finish with a quick, focused museum stop at the compact but excellent Franz Kafka Museum to catch one last cultural highlight before grabbing a takeaway ham-and-cheese chlebíček from Havelské tržiště market and heading to your departure.
Spend a relaxed final afternoon wandering the creative quarter around Holešovice, starting with a light lunch at Manifesto Market to try street-food versions of Czech classics, then browse contemporary Czech art and design at DOX Centre for Contemporary Art (check current exhibitions and the rooftop views). Finish with a slow riverside stroll along Libeňský ostrov or the quieter stretch of the Střelecký Island promenade, stopping for a last espresso and pastry at Café Letka before heading to collect luggage and depart.
Wind down your trip with a relaxed evening through the lively Vinohrady neighbourhood: start with small-plate dining at Bistro 8 to taste modern Czech flavors, then stroll the elegant tree-lined streets to the intimate cocktail bar Hemingway Bar for a signature drink. Finish with a peaceful late-night walk through Riegrovy Sady to enjoy city lights and a final panoramic view before returning to collect luggage and head to your departure.