Rise early in Como and catch the EuroCity train to Milano Centrale, then transfer to a Swiss-bound service through scenic Lombardy; enjoy a quick espresso at Pasticceria Monti on arrival to fuel the long day. From Milan Centrale, board the Bernina/InterCity connection toward Spiez, changing for the panoramic route to Interlaken Ost - soak in lake-and-alpine views from the carriage and grab a window seat for photos as you pass Brienz Lake and the valley farms.
After arriving into the Bernese Oberland corridor, transfer at Interlaken Ost and board the cogwheel toward Grindelwald Terminal, then switch to the Eiger Express gondola for a dramatic ascent under the Eiger's north face-take in sweeping views of Eiger Glacier and the deep Lauterbrunnen valley. Pause at Kleine Scheidegg for a hot chocolate on the sunny terrace, stroll short alpine paths to photograph the trilogy of peaks, then continue up to Jungfraujoch where you'll visit the ice tunnel and the Sphinx Terrace before descending in time for an evening connection back toward Lake Como.
After descending from the high Alps, unwind with a relaxed transfer stop in Lauterbrunnen village for a stroll beneath its towering waterfalls and a late-afternoon snack at Café Trümmelbach near the valley station. Continue your journey southward with a scenic rail connection that includes a pause in Spiez for a lakeside aperitif on the terrace of Häppi while watching the sun sink over the vineyards, then board your evening EuroCity back toward Milan and onward to Lake Como, savoring alpine-to-lake panoramas as the day softens into twilight.