Leave Avignon TGV around 05:30–06:30, allowing roughly 6–7 hours to reach Lourdes with a connection—typically via Montpellier, Toulouse, or another southern-French hub depending on the 2027 timetable. Book as soon as tickets open, since the fastest combinations may involve separate TGV and Intercités services; check the exact connection and allow a comfortable transfer window. Bring breakfast for the train, as onboard catering is limited. From Lourdes station, the sanctuary is about a 15–20-minute walk downhill, or a short local taxi ride if carrying luggage; taxis are especially useful on arrival with a tight afternoon schedule.
Head first to the Sanctuaires Notre-Dame de Lourdes, allowing about 2½ hours for the Grotte de Massabielle, Basilique du Rosaire, and Basilique de l’Immaculée-Conception. The sanctuary grounds are free and generally accessible throughout the day, though Mass, confession, baths, and candle services follow changing schedules—check the official program shortly before travel. Keep the visit unhurried: the Grotto is most meaningful when approached quietly, and March can be cool and wet, so waterproof shoes and a warm layer are worthwhile. Continue to the nearby Basilique Saint-Pie X, the vast underground church, for around 45 minutes; if a scheduled Mass fits, arrive 15–20 minutes early, otherwise use the space for quiet prayer.
Walk a few minutes to the Musée de Cire de Lourdes, where a one-hour visit follows the story of Bernadette and the Lourdes pilgrimage through detailed tableaux; allow roughly €8–12 for admission and verify the March opening hours, as seasonal hours can be shorter. For dinner, continue into central Lourdes to Le Palacio, a relaxed choice where a main course and drink typically come to about €20–35 per person; reserve or arrive early, especially on a Saturday evening. Afterward, take a 45-minute walk across Pont Vieux and through the old town, pausing for views toward Château fort de Lourdes lit against the hillside. The route is atmospheric but partly cobbled and can be slippery after rain; return to your hotel or Lourdes station by taxi if your accommodation is uphill or if you have an early departure the next morning.