It's recommended to rent a car for this itinerary, as most locations are a bit spread out. Expect about 30 minutes drive time between each location.
If you have more time, consider exploring nearby Pasadena, known for its historic architecture and art scene. For a shorter itinerary, skip Hidden Truth Distillery and spend more time at San Gabriel Mountains National Monument.
The closest airport to Arcadia is the Bob Hope Airport (BUR) in Burbank, about 30 minutes away by car. The larger Los Angeles International Airport (LAX) is about an hour away by car.