Start your first day in Rome by exploring the charming Trastevere neighborhood. Wander through its narrow cobblestone streets and admire the colorful buildings covered in ivy. Visit Basilica di Santa Maria in Trastevere, a beautiful 12th-century church with stunning mosaics and frescoes. Next, visit the Villa Farnesina, a Renaissance villa filled with beautiful frescoes by famous artists like Raphael. Enjoy a delicious lunch at Da Enzo al 29, a cozy restaurant serving traditional Roman cuisine. In the afternoon, visit the Botanical Garden of Rome to escape the bustling city and enjoy the beautiful garden and greenhouses filled with exotic plants.
For your second day in Rome, start by visiting the Vatican Museums, where you can admire world-famous masterpieces such as Michelangelo's Sistine Chapel ceiling. Afterward, visit the magnificent St. Peter's Basilica, the largest church in the world. Climb to the top of the cupola for breathtaking views over Rome. Have lunch at Trattoria da Enzo al 26, a local restaurant serving delicious pizza and pasta. In the afternoon, explore the Castel Sant'Angelo, a historic fortress that served as a prison, castle, and museum throughout the centuries.
If you have more time, you can add a visit to the Pantheon, the ancient Roman temple dedicated to the gods that now serves as a church, or explore the Roman Forum, the ancient plaza surrounded by ruins of important government buildings. On the other hand, if you have less time, you can skip the Castel Sant'Angelo or the Botanical Garden. Remember to wear comfortable shoes, drink plenty of water, and beware of pickpockets in crowded areas.