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12-Day Italy and Greece Itinerary: Milan, Venice, Rome, Athens, and Santorini
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12-Day Italy and Greece Itinerary: Milan, Venice, Rome, Athens, and Santorini
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Day 1: Explore Milan
Milan, Italy on May 20, 2025
9:00AM
Breakfast at Pavé
Enjoy a classic Italian pastry and coffee at Pavé, a famous Milanese bakery known for its fresh croissants and cappuccinos.
EUR10, 1 hour
10:30AM
Visit Milan Cathedral (Duomo di Milano)
Explore this iconic Gothic cathedral including rooftop terraces with panoramic city views. Open 9:00AM–7:00PM.
EUR15, 2 hours
1:00PM
Lunch at Luini
Taste traditional Panzerotti, a classic Milanese street food near the Duomo. Open 11:00AM–8:00PM.
EUR8, 1 hour
2:30PM
Visit Sforza Castle
Tour the Renaissance fortress with museums exhibiting art and history. Open 9:00AM–5:30PM.
EUR10, 2 hours
6:00PM
Dinner at Ratanà
Savor modern Milanese cuisine with a warm ambiance in Porta Nuova.
EUR40, 2 hours
Find Hotels in Milan
Day 2: Vanishing Venice
Venice, Italy on May 21, 2025
7:30AM
Train from Milan to Venice
Take a morning high-speed train to Venice (approx. 2.5 hours), arriving before lunch.
EUR40, 2.5 hours
11:30AM
Lunch at Osteria alle Testiere
Enjoy fresh seafood in this intimate Venetian spot. Open 12:00PM–3:00PM.
EUR35, 1.5 hours
1:30PM
Visit St. Mark’s Basilica
See Byzantine mosaics in this landmark basilica. Open 9:30AM–5:00PM.
EUR5, 1.5 hours
3:30PM
Explore Doge's Palace
Discover Venetian history and art in the grand palace. Open 9:00AM–7:00PM.
EUR25, 2 hours
6:00PM
Gondola Ride
Experience a classic gondola ride through Venice’s canals.
EUR80, 0.5 hours
7:30PM
Dinner at Antiche Carampane
Relish authentic Venetian cuisine in a historic setting. Open 7:00PM–11:00PM.
EUR50, 2 hours
Find Hotels in Venice
Day 3: Venice to Rome
Venice to Rome, Italy on May 22, 2025
9:00AM
Breakfast at Pasticceria Tonolo
Start with Venetian pastries and coffee at a popular historic café.
EUR10, 1 hour
10:30AM
Visit Peggy Guggenheim Collection
Explore modern art in this museum located in the former home of Peggy Guggenheim. Open 10:00AM–6:00PM.
EUR15, 2 hours
1:00PM
Lunch at Trattoria alla Madonna
Enjoy traditional Venetian dishes near Rialto Bridge. Open 12:00PM–3:00PM.
EUR30, 1.5 hours
3:30PM
Train from Venice to Rome
Take a high-speed train to Rome (approx. 3.5 hours), arrive early evening.
EUR50, 3.5 hours
7:30PM
Dinner at Trattoria da Enzo al 29
Savor classic Roman dishes in lively Trastevere, open 7:00PM–11:00PM.
EUR35, 2 hours
Find Hotels in Venice to Rome
Day 4: Ancient Rome
Rome, Italy on May 23, 2025
8:00AM
Breakfast at Roscioli Caffè
Enjoy great coffee and pastries near Campo de’ Fiori.
EUR12, 1 hour
9:30AM
Colosseum and Roman Forum
Explore the iconic Colosseum and Roman Forum ruins with guided tickets. Open 8:30AM–7:00PM.
EUR20, 3 hours
1:00PM
Lunch at La Taverna dei Fori Imperiali
Classic Roman food just steps from the Forum. Open 12:00PM–3:00PM.
EUR30, 1.5 hours
3:00PM
Pantheon and Piazza Navona
See the magnificent Pantheon and enjoy lively Piazza Navona. Pantheon open 9:00AM–7:00PM, ticket EUR5.
EUR5, 2 hours
6:00PM
Dinner at Osteria dell’Ingegno
Enjoy refined Roman cuisine in the city center, open 7:00PM–11:00PM.
EUR40, 2 hours
Find Hotels in Rome
Day 5: Vatican & Fly to Athens
Rome, Italy to Athens, Greece on May 24, 2025
7:30AM
Breakfast at Pasticceria Regoli
Quick Italian pastries before Vatican visit.
EUR8, 0.5 hours
8:30AM
Vatican Museums and Sistine Chapel
Pre-book tickets to visit world-class art and Michelangelo’s ceiling. Open 9:00AM–6:00PM.
EUR30, 3 hours
12:00PM
Lunch near Vatican at Ristorante Arlu
Cozy Roman dishes near the Vatican. Open 12:00PM–3:00PM.
EUR30, 1.5 hours
3:00PM
Fly Rome to Athens
Afternoon flight to Athens (about 2 hours), arriving early evening.
EUR120, 2 hours
6:30PM
Dinner at Strofi Restaurant
Dine with Acropolis views and authentic Greek cuisine, open evenings.
EUR50, 2 hours
Find Hotels in Rome
Day 6: Discover Athens
Athens, Greece on May 25, 2025
8:00AM
Breakfast at Meliartos
Enjoy classic Greek pastries and coffee near Syntagma Square.
EUR15, 1 hour
9:00AM
Visit Acropolis and Parthenon
Tour Athens’ ancient citadel and the iconic Parthenon. Open 8:00AM–7:00PM.
EUR20, 3 hours
12:30PM
Lunch at Dionysos Zonar's
Upscale Greek cuisine with spectacular Acropolis views. Open 12:00PM–4:00PM.
EUR45, 1.5 hours
2:30PM
Visit the Acropolis Museum
Explore archaeological finds from the Acropolis. Open 9:00AM–7:00PM.
EUR10, 2 hours
6:00PM
Stroll Plaka District
Wander picturesque streets with shops and tavernas, perfect for sunset.
Free, 2 hours
8:00PM
Dinner at Taverna Klimataria
Traditional Greek dishes with live music in a welcoming atmosphere.
EUR35, 2 hours
Find Hotels in Athens
Day 7: Athens to Santorini
Athens to Santorini, Greece on May 26, 2025
7:30AM
Breakfast at Taf Coffee
Start with specialty coffee and fresh pastries in central Athens.
EUR15, 1 hour
9:30AM
Morning flight to Santorini
Fly from Athens to Santorini (approx. 45 minutes), arrive before noon.
EUR80, 1 hour
11:30AM
Check in & Lunch at Kastro Oia Restaurant
Enjoy traditional Greek dishes with stunning caldera views in Oia.
EUR40, 1.5 hours
1:30PM
Explore Oia Village
Wander through whitewashed buildings and incredible sea views.
Free, 3 hours
6:30PM
Sunset Viewing and Dinner at Ambrosia
Dine with Oia’s famous sunset as your backdrop, fine Greek dining.
EUR50, 2 hours
Find Hotels in Athens to Santorini
Day 8: Santorini Volcano & Beach
Santorini, Greece on May 27, 2025
8:00AM
Breakfast at Pelican Kipos
Relax with breakfast in Fira’s garden café.
EUR15, 1 hour
9:30AM
Boat Tour to Nea Kameni Volcano and Hot Springs
Set out on a 3-4 hour tour hiking the volcano and bathing in hot springs.
EUR40, 4 hours
2:00PM
Lunch at Metaxi Mas
Enjoy a meal featuring Cretan-inspired Greek dishes, open afternoons.
EUR30, 1.5 hours
4:00PM
Relax or Winery Visit
Free time to unwind or visit a local Santorini winery.
Varies, Flexible
7:30PM
Dinner at Argo Restaurant
Dine on Mediterranean cuisine with caldera views in Fira.
EUR45, 2 hours
Find Hotels in Santorini
Day 9: Santorini & Evening Flight to Rome
Santorini to Rome on May 28, 2025
8:00AM
Breakfast at Passaggio Café
Start your day with local Greek breakfast specialties.
EUR15, 1 hour
10:30AM
Free morning in Santorini
Optional sightseeing, shopping, or relaxing by the hotel pool.
Varies, 3 hours
2:00PM
Lunch at Pelekanos
Cozy taverna with excellent Greek dishes near Fira center.
EUR30, 1.5 hours
5:00PM
Fly from Santorini to Rome
Evening flight back to Rome (approx. 2 hours).
EUR100, 2 hours
8:30PM
Light Dinner/Romantic Walk in Rome
Enjoy a light meal and nighttime stroll near the Trevi Fountain.
EUR20, 1.5 hours
Find Hotels in Santorini to Rome
Day 10: Rome Sightseeing Wrap-up
Rome, Italy on May 29, 2025
8:00AM
Breakfast at Forno Campo de' Fiori
Tasty Italian bakery specialties before a day of sightseeing.
EUR10, 1 hour
9:30AM
Visit Trevi Fountain and Spanish Steps
Enjoy iconic Roman landmarks in the morning light.
Free, 2 hours
12:00PM
Lunch at Roscioli Salumeria
Delicious Roman dishes in a relaxed, gourmet deli style setting.
EUR35, 1.5 hours
2:00PM
Villa Borghese Gardens and Gallery
Stroll beautiful gardens and optionally visit the Borghese Gallery. Open 9:00AM–7:00PM.
EUR15, 2 hours
5:00PM
Relax at Piazza Navona Café
Enjoy an espresso or gelato while people-watching in this lively square.
EUR8, 1 hour
7:30PM
Farewell Dinner at Enoteca Ferrara
Celebrate your trip with fine regional dishes and wines in Trastevere.
EUR50, 2 hours
Find Hotels in Rome
Day 11: Departure Day
Rome, Italy on May 30, 2025
8:00AM
Breakfast at a local café
Enjoy a leisurely breakfast to prepare for your departure.
EUR10, 1 hour
10:00AM
Transfer to Rome Airport
Head to the airport for your flight home, concluding your Italy and Greece adventure.
Varies, Variable
Find Hotels in Rome
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Itinerary created by
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April 17, 2025
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