Take the FEX Airport Express to Berlin Hauptbahnhof then U2 to Hausvogteiplatz for a quick walk to the hostel, or choose the S9 route via Alexanderplatz - both options cost €3.80.
Explore world-class museums including Pergamon Museum, Neues Museum, and Altes Museum using the €19 Museum Pass; plan 2-3 hours here for art and history.