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10-Day Eastern Sicily Wine, Culture, and Culinary Road Trip from Palermo
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10-Day Eastern Sicily Wine, Culture, and Culinary Road Trip from Palermo
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Day 1: Palermo Arrival
Palermo, Italy on September 28, 2025
3:00pm
Check-in at Hotel Palazzo Brunaccini
A stylish hotel in the historic centre, perfect for exploring Palermo's cultural gems.
EUR120, 1h
4:00pm
Visit Palermo Cathedral
Explore Palermo's iconic cathedral featuring diverse architectural styles, reflecting the city's rich history.
EUR5, 1h
6:00pm
Evening Stroll through Quattro Canti
Enjoy the lively historic square known for its beautiful Baroque architecture and fountains.
Free, 30m
7:30pm
Dinner at Antica Focacceria San Francesco
Savour traditional Sicilian street food like arancini and panelle at this beloved eatery open until 11 pm.
EUR30, 1h30m
Find Hotels in Palermo
Day 2: Palermo Culture
Palermo, Italy on September 29, 2025
8:30am
Breakfast at Pasticceria Cappello
Start the day with Sicilian pastries such as cannoli or cassata at this renowned pastry shop.
EUR8, 1h
9:30am
Palazzo dei Normanni and Palatine Chapel
Explore the Norman palace with stunning mosaics in the Palatine Chapel, a masterpiece of Arab-Norman art.
EUR12, 2h
12:00pm
Lunch at Osteria dei Vespri
Enjoy fresh seafood and Sicilian cuisine in a cosy setting, open from noon.
EUR35, 1h30m
2:00pm
Visit Mercato di Ballarò
Experience Palermo’s bustling street market, perfect for local products and lively atmosphere.
Free, 1h
4:00pm
Drive to Cefalù
A scenic 1hr drive east to the charming coastal town of Cefalù.
Fuel approx. EUR10, 1h
5:30pm
Check-in at Hotel Le Calette
A stunning seaside hotel with panoramic views of the Tyrrhenian Sea.
EUR140, 30m
7:30pm
Dinner at Ristorante La Brace
Dine on grilled specialties and fresh seafood, enjoying open-air dining near the beach.
EUR40, 2h
Find Hotels in Palermo
Day 3: Cefalù History & Wine
Cefalù, Italy on September 30, 2025
8:00am
Breakfast at Hotel
Enjoy a breakfast buffet with local Sicilian produce and pastries overlooking the sea.
Included, 1h
9:30am
Visit Cefalù Cathedral
Discover this impressive Norman cathedral known for its Byzantine mosaics, open 9am-5pm.
EUR6, 1h
11:00am
Hike La Rocca
Climb the iconic rock overlooking Cefalù for panoramic views of town and coastline.
Free, 1h30m
1:00pm
Lunch at Ristorante Al Faro
Enjoy fresh fish dishes paired with local wines in this highly rated seafood restaurant.
EUR35, 1h30m
3:00pm
Wine Tasting at Azienda Agricola Fazio
Short drive to a nearby winery for a tasting of Sicilian wines, including Nero d'Avola and Grillo.
EUR25, 2h
6:00pm
Relax at Hotel or Beach
Spend your evening relaxing at the hotel or strolling the beach promenade.
Free, 2h
8:00pm
Dinner at Il Normanno
An authentic Sicilian restaurant in Cefalù's old town serving local classics made from family recipes.
EUR40, 2h
Find Hotels in Cefalù
Day 4: Taormina Scenic Charm
Taormina, Italy on October 1, 2025
8:00am
Breakfast and Check-out
Enjoy a leisurely breakfast before driving east to Taormina (approx 1.5 hours).
Included + Fuel EUR15, 2h
11:00am
Check-in at Hotel Villa Carlotta
A luxurious hotel offering spectacular views over Mount Etna and the sea.
EUR150, 30m
12:00pm
Lunch at Trattoria Don Ciccio
Sample Sicilian and Mediterranean dishes in this charming eatery located in historic Taormina.
EUR30, 1h
1:30pm
Visit Ancient Theatre of Taormina
Explore the well-preserved Greco-Roman theatre with breathtaking views over the coastline, open 9am-6pm.
EUR10, 1h30m
3:30pm
Walk Corso Umberto
Stroll the elegant main street with boutiques, cafes, and historical buildings.
Free, 1h
5:00pm
Wine Tasting at Duca di Salaparuta
Visit this esteemed winery near Etna for a tasting session highlighting local volcanic terroir wines.
EUR30, 2h
7:30pm
Dinner at Ristorante La Capinera
Michelin-starred restaurant offering exquisite Sicilian cuisine with great views and ambience.
EUR70, 2h
Find Hotels in Taormina
Day 5: Mount Etna & Nature
Mount Etna region, Italy on October 2, 2025
8:00am
Breakfast at Hotel
Enjoy your hotel breakfast before heading out for a day of exploration on Mount Etna.
Included, 1h
9:00am
Mount Etna Guided Tour
Join a guided 4-hour hike or jeep tour exploring volcanic craters and unique landscapes, bookings recommended.
EUR60, 4h
1:30pm
Lunch at Rifugio Sapienza
Mountain refuge restaurant serving hearty Sicilian dishes perfect after the Mount Etna adventure.
EUR25, 1h
3:00pm
Visit to Cantina Russo Winery
Discover a family-owned vineyard on the slopes of Etna for a wine tasting and cellar tour experience.
EUR25, 2h
6:00pm
Return to Taormina
Relax back at hotel after a full day of Etna exploration.
Fuel EUR10, 1h
8:00pm
Dinner at Osteria Nero D'Avola
Enjoy a selection of local wines paired with traditional dishes in cosy surroundings within Taormina.
EUR40, 2h
Find Hotels in Mount Etna region
Day 6: Syracuse Ancient Charm
Syracuse, Italy on October 3, 2025
8:00am
Breakfast at Hotel and check-out
Prepare for your journey to Syracuse (approx 1 hour drive).
Included + Fuel EUR10, 1h30m
10:00am
Check-in at Algilà Ortigia Charme Hotel
A charming boutique hotel in the heart of Ortigia Island, perfect for exploring Syracuse.
EUR130, 30m
11:00am
Explore Neapolis Archaeological Park
Visit the ancient Greek theatre, Roman amphitheatre, and the Ear of Dionysius, open 9am-7pm.
EUR10, 2h
1:30pm
Lunch at Don Camillo
Enjoy Sicilian seafood, fresh caught and prepared in traditional style on Ortigia Island.
EUR35, 1h30m
3:00pm
Walking tour of Ortigia Island
Discover baroque architecture, piazzas, and the vibrant market area with artisanal shops.
Free, 2h
6:00pm
Relax at hotel or visit local wine bar Vino e Cuccuma
Sample Sicilian wines and cheeses in a cosy setting in Ortigia.
EUR20, 1h30m
8:00pm
Dinner at Apollonion Osteria da Carlo
Classic Sicilian dishes with a modern twist in a welcoming atmosphere, open till 11pm.
EUR40, 2h
Find Hotels in Syracuse
Day 7: Syracuse & Island Leisure
Syracuse, Italy on October 4, 2025
8:30am
Breakfast at Hotel
Enjoy a Sicilian breakfast with local fruits and pastries.
Included, 1h
9:30am
Boat Tour Around Ortigia
Take a 2-hour boat tour to see the coastline, caves and views of the cathedral from the sea.
EUR30, 2h
12:00pm
Lunch at Caseificio Borderi
Sample fresh cheeses and antipasti from this famous deli, great for a light, authentic lunch.
EUR20, 1h
1:30pm
Visit Museo Paolo Orsi
Explore one of Italy’s most important archaeological museums, open 9am-7pm.
EUR8, 2h
4:00pm
Relax in Ortigia’s Piazza del Duomo
People-watch and enjoy a coffee or gelato in the heart of the city.
EUR5, 1h
7:00pm
Dinner at Sicilia in Tavola
Enjoy homely Sicilian cuisine with local wines in a sophisticated setting.
EUR45, 2h
Find Hotels in Syracuse
Day 8: Noto Baroque Beauty
Noto, Italy on October 5, 2025
8:00am
Breakfast and Check-out
Leave Syracuse and drive approx 40 mins to Noto, the baroque jewel of Sicily.
Included + Fuel EUR5, 1h30m
10:00am
Check-in at Gagliardi Boutique Hotel
Elegant accommodation in the historic centre, ideal for exploring Noto’s famous architecture.
EUR110, 30m
10:45am
Walking Tour of Noto
Marvel at Noto Cathedral, Palazzo Nicolaci and other UNESCO Baroque landmarks.
Free, 2h
1:00pm
Lunch at Ristorante Dammuso
Savour creative Sicilian dishes using local ingredients, with a good wine list.
EUR35, 1h30m
3:00pm
Visit to Feudo Maccari Winery
Enjoy a wine tasting and vineyard tour focusing on Nero d'Avola varietals near Noto.
EUR30, 2h
6:00pm
Relax at hotel
Freshen up and enjoy hotel amenities before dinner.
Free, 1h
8:00pm
Dinner at Manna Noto
A stylish restaurant offering sophisticated Sicilian cuisine with excellent wine pairings.
EUR50, 2h
Find Hotels in Noto
Day 9: Leisure & Return to Palermo
Noto to Palermo, Italy on October 6, 2025
8:00am
Breakfast and Relax in Noto
Enjoy a leisurely morning breakfast and take a final walk around town.
Included, 2h
10:30am
Drive back to Palermo
Approximately 3.5-hour drive back north to Palermo with scenic Sicilian landscapes en route.
Fuel approx. EUR30, 3h30m
2:30pm
Check-in at Grand Hotel Wagner, Palermo
Elegant 4-star hotel close to main attractions, ideal to relax before last day.
EUR140, 30m
3:30pm
Visit Teatro Massimo
Explore Italy’s largest opera house and enjoy architecture and possibly an afternoon tour.
EUR8, 1h
5:00pm
Coffee and Pastries at Pasticceria Oscar
Enjoy an elegant coffee break with sweet Sicilian treats.
EUR10, 30m
7:30pm
Farewell Dinner at Bye Bye Blues
Celebrate your Sicilian journey with a sophisticated dining experience featuring seafood specialties.
EUR60, 2h
Find Hotels in Noto to Palermo
Day 10: Departure
Palermo, Italy on October 7, 2025
8:00am
Breakfast at Hotel
Enjoy a final breakfast in Palermo before your departure.
Included, 1h
10:00am
Return rental car and airport transfer
Head to Palermo Airport for departure; allow at least 2 hours before flight time.
Fuel and rental return fees approx. EUR20, 1h
Find Hotels in Palermo
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Itinerary created by
Plantrip Team
June 2, 2025
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