12-Day Iconic Italy Itinerary Including Stay at NYX Hotel Milano: Milan, Florence, Naples & Rome

Day 1: Milan Arrival & Exploration

Milan, Italy on June 24, 2025

8:00am

Breakfast at Pavé

Start your day with a delicious Italian breakfast at Pavé, famous for its fresh pastries and expertly crafted coffee, open from 7:30am to 7:30pm. Conveniently reachable from NYX Hotel Milano.
EUR10, 1h

9:30am

Duomo di Milano

Visit Milan’s iconic Gothic cathedral located approximately 15 minutes by metro from NYX Hotel Milano. Climb to the rooftop terraces to enjoy breathtaking panoramic city views. The cathedral is open from 9:00am to 7:00pm with ticket purchase required.
EUR15, 2h

12:00pm

Lunch at Luini

Savor the famous panzerotti at Luini, a popular fast-eat spot just a short walk from the Duomo. Open daily from 10:00am to 8:00pm.
EUR8, 1h

1:30pm

Galleria Vittorio Emanuele II

Explore this historic and elegant 19th-century shopping arcade with luxury stores and cafés. Open all day and very close to Luini and the Duomo.
Free, 1h

3:00pm

Sforza Castle

Tour the Renaissance fortress housing several museums and art collections. Approximate metro ride 20 minutes from Duomo. Open 9:00am to 5:30pm.
EUR10, 2h

6:30pm

Dinner at Ristorante Nabucco

Experience traditional Milanese cuisine in the lively Brera district, about a 10-minute taxi ride from your hotel. Open from 7:00pm onwards.
EUR40, 2h
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Day 2: Milan Art & Parks

Milan, Italy on June 25, 2025

8:00am

Breakfast at Marchesi 1824

Enjoy an elegant breakfast at the historic pastry shop Marchesi 1824, just a short taxi or metro ride from NYX Hotel Milano. Open 7:30am to 7:30pm.
EUR15, 1h

9:30am

Leonardo da Vinci's Last Supper

Visit the Convent of Santa Maria delle Grazie to see the famous mural by Leonardo da Vinci. Advanced booking is essential. Open 8:15am to 7:00pm, approximately 25 minutes by metro from hotel.
EUR20, 1h

11:00am

Brera Art Gallery

Explore outstanding Renaissance and Baroque art in the Brera district near your dinner location from prior day. Open 8:30am to 7:15pm Tuesday to Sunday.
EUR12, 2h

1:30pm

Lunch at Osteria del Binari

Taste classic Milanese dishes in a charming atmosphere with a garden courtyard, located about 20 minutes by taxi from hotel. Open noon to 3pm.
EUR35, 1.5h

3:30pm

Parco Sempione

Take a relaxing walk through this large public park behind Sforza Castle, easily accessible by metro or bus from your accommodation.
Free, 1.5h

6:00pm

Aperitivo at Nottingham Forest

Experience Milan’s famous aperitivo scene with inventive cocktails and small plates. About 15 minutes by taxi from hotel, open 6pm to 1am.
EUR20, 2h

8:30pm

Dinner at Ratana

Delight in modern Milanese cuisine near Parco Sempione, roughly a 20-minute taxi ride from hotel. Open from 7pm to 11pm.
EUR45, 2h
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Day 3: Milan to Florence & Arrival

Milan to Florence, Italy on June 26, 2025

7:30am

Breakfast at NYX Hotel Milano

Enjoy a convenient and hearty breakfast at your hotel before your departure.
Included, 1h

9:00am

Travel to Florence by Train

Take a high-speed Trenitalia or Italo train from Milan Centrale station (20 min taxi from NYX Hotel) to Florence Santa Maria Novella in about 2 hours.
EUR40, 2h

12:00pm

Check-in and Lunch at Trattoria Mario

Enjoy traditional Tuscan specialties in this popular Florentine eatery open from 12pm to 3pm, closed Sundays.
EUR25, 1.5h

2:00pm

Florence Cathedral & Baptistery

Visit the UNESCO World Heritage site with magnificent dome and baptistery. Open 10am to 5pm.
EUR18, 2h

4:30pm

Ponte Vecchio

Walk along the historic bridge lined with shops; open all day, perfect for shopping and photography.
Free, 1h

6:00pm

Dinner at Osteria Vini e Vecchi Sapori

Indulge in authentic Tuscan dishes at this rustic spot, open 7pm to 11pm.
EUR40, 2h
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Day 4: Florence Museums & Gardens

Florence, Italy on June 27, 2025

8:00am

Breakfast at Ditta Artigianale

Start your day with specialty coffee and light breakfast at this popular café, open 8am to 7pm.
EUR12, 1h

9:30am

Uffizi Gallery

Marvel at masterpieces by Botticelli, Da Vinci and others. Open 8:15am to 6:50pm Tuesday to Sunday; pre-book tickets.
EUR20, 3h

1:00pm

Lunch at Mercato Centrale

Sample a variety of Tuscan specialties and street food in this lively indoor market. Open 10am to midnight.
EUR20, 1.5h

3:00pm

Boboli Gardens

Wander through beautiful gardens and sculptures behind Pitti Palace, open 8:15am to 7:30pm.
EUR10, 2h

6:00pm

Sunset at Piazzale Michelangelo

Take in sweeping views of Florence’s skyline at sunset. Open all day, accessible by short taxi or walk.
Free, 1h

7:30pm

Dinner at La Giostra

Enjoy a romantic setting and exceptional Tuscan cuisine, open 7pm to 11pm.
EUR50, 2h
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Day 5: Florence to Naples Travel

Florence to Naples, Italy on June 28, 2025

7:30am

Breakfast near hotel

Have a quick breakfast near your accommodation before departure, options available from 7am.
EUR10, 0.5h

8:30am

Train from Florence to Naples

Board a high-speed train from Florence Santa Maria Novella to Naples Centrale, journey about 3 hours.
EUR50, 3h

12:00pm

Check-in and Lunch at Pizzeria Brandi

Taste authentic Neapolitan pizza at the historic Pizzeria Brandi, open 12pm to 11pm.
EUR25, 1.5h

2:00pm

Naples National Archaeological Museum

Explore artifacts from Pompeii and Herculaneum. Open 9am to 7:30pm Tuesday to Sunday.
EUR15, 2h

4:30pm

Walk along Lungomare Caracciolo

Enjoy a seaside promenade with views of Mount Vesuvius, perfect for a relaxing stroll.
Free, 1.5h

7:00pm

Dinner at Da Michele

End your day with a legendary Neapolitan pizza at Da Michele, open 6:30pm to 11:30pm.
EUR20, 2h
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Day 6: Pompeii Day Trip

Naples/Pompeii, Italy on June 29, 2025

7:30am

Breakfast at Gran Caffè Gambrinus

Historic café serving delightful pastries and espresso, open 7am to 10pm.
EUR15, 1h

8:30am

Train to Pompeii

Take the Circumvesuviana train from Naples to Pompeii in 30 minutes, tickets cost EUR4 round trip.
EUR4, 0.5h

9:00am

Pompeii Ruins Tour

Spend four hours touring this extraordinary archaeological site open 9am to 7:30pm.
EUR18, 4h

1:30pm

Lunch at Caupona Pompeii Restaurant

Dine on Roman-inspired dishes near the site, open 12pm to 3pm.
EUR30, 1.5h

3:30pm

Return to Naples and visit Castel dell'Ovo

Explore the oldest standing fortification in Naples with panoramic bay views, open 9am to 7pm.
Free, 1.5h

6:30pm

Dinner at Palazzo Petrucci

Indulge in upscale modern Neapolitan cuisine, open 7pm to 11pm.
EUR60, 2h
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Day 7: Naples to Rome Travel

Naples to Rome, Italy on June 30, 2025

7:30am

Breakfast at Gran Caffè Gambrinus

Savor delicious coffee and pastries before departure, open 7am to 10pm.
EUR15, 1h

9:00am

Train from Naples to Rome

Travel by high-speed train from Naples Centrale to Rome Termini in about 1 hour and 10 minutes.
EUR40, 1h 10m

11:00am

Check-in and Lunch near Piazza Navona

Dine at Ristorante Santa Cristina al Quirinale, offering classic Roman dishes, open 12pm to 3pm.
EUR35, 1.5h

1:30pm

Pantheon

Visit the remarkably well-preserved Roman temple, open 9am to 7pm.
EUR5, 1h

3:00pm

Piazza Navona

Explore the lively square with Baroque fountains, artists and nearby cafés, open throughout the day.
Free, 1h

4:00pm

Trevi Fountain

Toss a coin into Rome’s most famous fountain, always accessible.
Free, 30m

6:30pm

Dinner at Trattoria Da Enzo al 29

Typical Roman dining experience in the Trastevere district, open 7pm to 11pm.
EUR40, 2h
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Day 8: Rome Ancient History

Rome, Italy on July 1, 2025

8:00am

Breakfast at Roscioli Caffè

Enjoy coffee and pastries at this highly regarded Roman café, open 7:30am to 8:30pm.
EUR15, 1h

9:00am

Colosseum & Roman Forum

Explore the legendary amphitheater and surrounding ruins. Pre-book tickets for early entrance; open 8:30am to 7pm.
EUR18, 3h

12:30pm

Lunch at La Carbonara

Enjoy classic Roman pasta dishes in the Monti neighborhood, open 12pm to 3pm.
EUR30, 1.5h

2:30pm

Palatine Hill

Visit the birthplace of Rome with archaeological ruins and gardens; admission included with Colosseum ticket.
Included, 1.5h

5:00pm

Capitoline Museums

Discover Roman art and artifacts atop Capitoline Hill; open 9:30am to 7:30pm.
EUR15, 2h

7:30pm

Dinner at Roscioli Restaurant

Indulge in expertly prepared Italian cured meats and pasta dishes at this renowned Roman restaurant, open 7pm to 11pm.
EUR50, 2h
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Day 9: Vatican & Trastevere

Rome, Italy on July 2, 2025

7:30am

Early Breakfast at Hotel

Enjoy a quick breakfast before the Vatican visit to maximize your day.
Included, 0.5h

8:00am

Vatican Museums & Sistine Chapel

See world-renowned art collections and Michelangelo’s masterpiece ceiling. Book skip-the-line tickets. Open 9am to 6pm.
EUR30, 3h

11:30am

St. Peter’s Basilica

Tour the largest church in the world and climb to the dome for amazing views. Open 7am to 7pm. Dome climb costs EUR10.
Free; EUR10 for dome climb, 2h

1:30pm

Lunch at Ristorante Arlù

Relax in Trastevere with classic Roman dishes in a cozy atmosphere. Open 12pm to 3pm.
EUR35, 1.5h

3:30pm

Explore Trastevere

Wander cobbled streets lined with vibrant shops and historic sights like Santa Maria in Trastevere basilica.
Free, 2h

6:00pm

Aperitivo at Freni e Frizioni

Enjoy a lively aperitivo with cocktails and small bites, open 6pm to 2am.
EUR20, 2h

8:30pm

Dinner at Cesare al Casaletto

Favored by locals for hearty traditional Roman dishes in a casual setting, open 7pm to 11pm.
EUR40, 2h
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Day 10: Rome Leisure & Departure

Rome, Italy on July 3, 2025

8:00am

Breakfast at Panella

Start your final day with exquisite bakery goods and coffee at Panella, open 7:30am to 8pm.
EUR15, 1h

9:30am

Villa Borghese Gardens and Gallery

Enjoy a morning walk in the beautiful gardens, and optionally tour the Borghese Gallery (pre-book tickets). Open 9am to 7pm.
Gallery EUR20, 3h

1:00pm

Lunch at Casina Valadier

Dine elegantly inside the Villa Borghese gardens overlooking Rome, open 12pm to 3pm.
EUR40, 1.5h

3:00pm

Last-minute Shopping & Spanish Steps

Visit luxury boutiques and relax by the iconic Spanish Steps before departure.
Free, 2h

6:00pm

Dinner at Il Gabriello

End your trip with classic Roman dishes near Piazza Navona, open 7pm to 11pm.
EUR45, 2h
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