Argentina and Chile Two-Week Itinerary - Late October 2025

Day 1: Arrival in Buenos Aires, Argentina

Morning: Arrive in Buenos Aires and check into your hotel. Take a gentle walk around the vibrant Plaza de Mayo to get your first glimpse of the city’s historic heart.

Afternoon: Explore San Telmo, the oldest neighborhood famous for its colonial buildings and antiques market. Enjoy a café lunch surrounded by local art.

Evening: Experience a traditional Tango show in La Boca, soaking up the passion and culture of Buenos Aires nightlife.

Day 2: Buenos Aires - Culture and Cuisine

Morning: Visit the impressive Teatro Colón for a guided tour, then stroll through the nearby Avenida Corrientes, known for its bookstores and theaters.

Afternoon: Enjoy Argentine cuisine with a lunch at Pierre Gagnaire’s inspired restaurant followed by a visit to the MALBA Museum for Latin American art.

Evening: Relax at Puerto Madero waterfront with dinner overlooking the river, trying some local seafood specialties.

Day 3: Fly to Mendoza, Argentina - Wine Region

Morning: Morning flight to Mendoza. Settle into your accommodation and prepare for some wine tasting adventures.

Afternoon: Take a guided tour of the Maipú wine region, visiting renowned wineries and learning about Malbec production.

Evening: Dine at a vineyard restaurant enjoying local dishes paired with Mendoza’s famous wines.

Day 4: Mendoza - Andes and Adventure

Morning: Head out early for a day trip into the Andes Mountains, visiting Aconcagua Provincial Park and taking in stunning mountain views.

Afternoon: Return to Mendoza and relax at the hotel or explore local shops and cafes.

Evening: Enjoy a casual dinner downtown with typical Argentine flavors like empanadas and asado.

Day 5: Mendoza to Santiago, Chile - Cross the Andes

Morning: Cross the Andes via bus or private transfer to Santiago, Chile. Marvel at the breathtaking landscapes along the route.

Afternoon: Arrive in Santiago and visit the Plaza de Armas and the historic center of the city.

Evening: Have dinner in the Bellas Artes neighborhood, known for its lively atmosphere and good restaurants.

Day 6: Santiago City Exploration

Morning: Take a cable car ride up Cerro San Cristóbal for panoramic views over Santiago and the Andes.

Afternoon: Visit the La Chascona museum, the former home of poet Pablo Neruda, and stroll through the Lastarria district.

Evening: Enjoy an evening in Providencia, sampling Chilean wines at a local bar.

Day 7: Day Trip to Valparaíso

Morning: Take a short trip to the colorful port city of Valparaíso, exploring its hillside neighborhoods and street art.

Afternoon: Ride the famous funiculars and visit the home of poet Pablo Neruda, La Sebastiana.

Evening: Return to Santiago and have a relaxing dinner near your hotel.

Day 8: Fly to Puerto Varas, Chile - Lake District

Morning: Fly to Puerto Montt and transfer to Puerto Varas, a charming town on Lake Llanquihue.

Afternoon: Walk along the lakeshore and visit the iconic Church of the Sacred Heart of Jesus with its German architecture.

Evening: Taste local cuisine including fresh lake trout at a lakeside restaurant.

Day 9: Vicente Pérez Rosales National Park

Morning: Explore Vicente Pérez Rosales National Park, including Petrohue Falls and panoramic views of Osorno Volcano.

Afternoon: Optional boat trip on Llanquihue Lake to enjoy surrounding scenery and wildlife.

Evening: Return to Puerto Varas and relax at a local café or brewery.

Day 10: Puerto Varas to El Calafate, Argentina - Patagonia

Morning: Fly to El Calafate, gateway to Patagonia’s glaciers.

Afternoon: Visit the Lago Argentino and explore the quaint town.

Evening: Enjoy Patagonian lamb or trout at a renowned local restaurant.

Day 11: Perito Moreno Glacier

Morning: Full-day tour to the spectacular Perito Moreno Glacier with opportunities for boardwalk walks and optional boat rides near the glacier walls.

Afternoon: Continue exploring the national park surroundings with guided commentary on the glacial formations.

Evening: Return to El Calafate for a quiet dinner and rest.

Day 12: El Calafate to Torres del Paine, Chile

Morning: Transfer to Torres del Paine National Park in Chile, renowned for dramatic mountain landscapes.

Afternoon: Begin short hikes to viewpoints such as Mirador Cuernos or visit the Salto Grande Waterfall.

Evening: Stay overnight at a lodge inside or near the park, enjoying Patagonian cuisine.

Day 13: Torres del Paine Hiking

Morning: Full day hiking to iconic spots like the Base of the Towers or the Lago Grey viewpoint.

Afternoon: Continue trekking or take a guided wildlife tour to spot guanacos and condors.

Evening: Relax with dinner at the lodge and stargaze under pristine skies.

Day 14: Return to Santiago & Departure

Morning: Transfer back to Punta Arenas for your flight to Santiago.

Afternoon: Depending on your flight schedule, enjoy last-minute shopping or a quick visit to Costanera Center, South America’s tallest building.

Evening: Depart Santiago for your journey home or onward travel.

Time and Cost Estimates

• Buenos Aires Tango Show – 3 hours – $50
• Mendoza Wine Tour (Maipú) – 5 hours – $80
• Andes Mountains Day Trip – 7 hours – $100
• Santiago Cable Car to Cerro San Cristóbal – 2 hours – $15
• Valparaíso Day Trip – 8 hours – $60
• Vicente Pérez Rosales National Park Excursion – 6 hours – $70
• Perito Moreno Glacier Tour – 8 hours – $120
• Torres del Paine National Park Hiking – Full day – $100

Total Estimated Cost: $595

Tips

If you prefer a more relaxed pace, consider extending your stay in Patagonia by 2-3 days to fully explore the Torres del Paine circuit with additional guided hikes and nature excursions. Conversely, if you want to reduce the trip duration, cut 2 days from the Lake District and Mendoza regions, concentrating more on Buenos Aires, Santiago, and Patagonia highlights.