Begin your Italian adventure by arriving at the magnificent Milano Centrale Railway Station from Paris and settling into the vibrant atmosphere of Italy's fashion capital. Head to the city center to stand in awe before the intricate Gothic spires of the Duomo di Milano, followed by a leisurely stroll through the sun-drenched Piazza del Duomo as the city wakes up.
Escape the midday heat by wandering beneath the luxurious glass-vaulted ceilings of the Galleria Vittorio Emanuele II for some window shopping and a traditional gelato. Afterward, make your way to the historic Castello Sforzesco to explore its expansive red-brick courtyards and the lush, shaded paths of the adjacent Sempione Park.
As the June sun sets, make your way to the lively Navigli District to experience the quintessential Milanese habit of aperitivo alongside the shimmering waters of the Naviglio Grande. End your first night with a moonlit stroll through the charming, cobblestone streets of the Brera District, ducking into a local trattoria for a late-night taste of authentic saffron-infused risotto.
Kick off your morning by ascending to the Duomo Terraces, where you can walk among the forest of white marble spires and enjoy a panoramic view of the city skyline. Afterward, immerse yourself in the epicenter of style at the Quadrilatero della Moda, strolling past the luxurious window displays of Via Montenapoleone and the historic Teatro alla Scala.
After a morning of high fashion, delve into history at the UNESCO-listed Santa Maria delle Grazie to marvel at Leonardo da Vinci's iconic mural, The Last Supper. Follow this with a visit to the ancient Basilica di Sant'Ambrogio, where you can explore the tranquil cloisters and admire the Byzantine-style mosaics of this Romanesque masterpiece.
Spend your second evening in the futuristic Porta Nuova district, marvelling at the award-winning Bosco Verticale as its lush balconies glow at twilight. Afterward, enjoy a chic dinner at the iconic 10 Corso Como concept store before ending the night watching the dancing water fountains under the dazzling lights of the Piazza Gae Aulenti.
Start your morning by uncovering the hidden gem of San Maurizio al Monastero Maggiore, where every inch of the interior is covered in vibrant Renaissance frescoes. Continue your architectural exploration at the Civic Archaeological Museum, where you can walk through tranquil cloisters and see the remains of the ancient Roman city walls and the Tower of Ansperto.
Visit the fascinating San Bernardino alle Ossa, home to an ossuary chapel artistically decorated with human bones that showcases a unique side of Milanese history. Afterward, immerse yourself in the city's futuristic side at the CityLife district, where you can walk among the sculptural skyscrapers designed by architectural legends Zaha Hadid and Daniel Libeskind.
Spend your final evening in Milan at the atmospheric Colonne di San Lorenzo, where sixteen ancient Roman columns provide a majestic backdrop for the city's vibrant nightlife and street performers. Afterward, wander through the historic Porta Ticinese gate to enjoy a farewell banquet at a local osteria, soaking in the authentic neighborhood charm before your high-speed train journey to Rome tomorrow.
Bid a fond farewell to Milan as you board a high-speed Frecciarossa train at the grand Milano Centrale railway station, settling in for a scenic journey through the rolling landscapes of Tuscany and Umbria. As you speed toward the south, enjoy a morning espresso while watching the Italian countryside fly by before finally pulling into the bustling Roma Termini station, the historic gateway to the Eternal City.
After dropping your bags, ease into the Eternal City with a visit to the nearby Piazza della Repubblica, where the grand semi-circular colonnades encircle the magnificent Fountain of the Nayads. Step inside the Basilica of Santa Maria degli Angeli e dei Martiri, uniquely designed by Michelangelo within the soaring vaults of the ancient Baths of Diocletian, before admiring the world-class Roman mosaics and sculptures at the [National Roman Museum - Palazzo Massimo](https://museonazionaleromano.beniculturali.it/en/palazzo-massimo/).
As the warm June evening sets in, wander toward the iconic Trevi Fountain to toss a coin into its crystalline waters under the glow of dramatic night-time illumination. Afterward, enjoy a sunset stroll up the Spanish Steps for a panoramic view of the city's terracotta rooftops before indulging in your first authentic Roman dinner in the lively streets surrounding Piazza di Spagna.
Start your morning by stepping back in time at the mighty Colosseum, where you can explore the ancient amphitheater's tiers while the early June sun illuminates the arena floor. Continue your journey into history by wandering through the sprawling archaeological treasures of the Roman Forum and ascending the Palatine Hill to view the remains of imperial palaces set against sweeping panoramas of the Eternal City.
After your descent from the hills, walk through the grand Piazza Venezia to admire the towering white marble of the Altare della Patria. Take the panoramic elevator to the Terrazza delle Quadrighe for breathtaking views of the city before exploring the nearby [Capitoline Museums](https://www.museicapitolini.org/en/informazioni_pratiche/biglietti_e_videoguide), home to the iconic bronze Capitoline Wolf. Conclude your afternoon by strolling past the ancient ruins of [Trajan's Market](https://www.mercatiditraiano.it/en/informazioni_pratiche/biglietti_e_videoguide), showcasing the architectural marvels of the Roman Empire's historic commercial hub.
As the warm Roman twilight descends, cross the river to the atmospheric Trastevere district, where narrow cobblestone alleys come alive with buzzing outdoor cafes and ivy-draped facades. Enjoy a traditional dinner in the shadow of the centuries-old Basilica of Santa Maria in Trastevere before taking a leisurely stroll across the ancient stone archway of Ponte Sisto to see the city lights shimmering on the Tiber.
Begin your final morning by entering the architectural wonder of the [Pantheon](https://portale.museiitaliani.it/), where the early sun filters through the iconic oculus to illuminate the ancient marble floor. Afterward, head to the elegant, oval-shaped Piazza Navona to admire the dramatic sculptures of Bernini's Fountain of the Four Rivers before the afternoon crowds arrive.
Spend your final afternoon crossing the Tiber to marvel at the massive colonnades of St. Peter's Square and the soaring facade of St. Peter's Basilica. Afterward, wander toward the riverside to explore the circular ramparts of [Castel Sant'Angelo](https://www.google.com/search?q=Castel+Sant%27Angelo+6+days+in+italy%2C+2+nights+in+milan%2C+2+nights+in+milan+and+2+nights+in+rome+in+june.+start+from+paris+in+june+2026+official+site) before enjoying a sunny stroll through the vibrant flower and produce stalls of the historic Campo de' Fiori.
For your final Italian evening, ascend to the Pincio Terrace above Piazza del Popolo to watch the sunset paint the Roman skyline in hues of gold and amber. Afterward, celebrate the conclusion of your journey with a traditional meal in the historic Jewish Ghetto, dining amidst the atmospheric ancient ruins of the Teatro di Marcello as the moonlight illuminates the Eternal City.