Most of the attractions in Rome are within walking distance of each other, so you should be able to get around on foot. For longer distances, consider taking the metro, which is cheap and efficient. A single metro ticket costs €1.50 and is valid for 100 minutes. Taxis are also available, but they can be expensive and are subject to traffic. A taxi ride from the airport to the city center costs around €48 and takes about 45 minutes.
If you have extra time, consider visiting The Spanish Steps or the Borghese Gallery. If you have less time, you can combine some of the attractions on this itinerary or skip some altogether. Be sure to wear comfortable shoes, as Rome's cobblestone streets can be hard on your feet. Remember to dress modestly when visiting churches and religious sites. Finally, be prepared for crowds, as Rome is a popular tourist destination. Try to visit popular attractions early in the morning or late in the day to avoid the biggest crowds.