Visit the Plaza Mayor and Mercado San Miguel.
Explore Reina Sofia Museum and Thyssen-Bornemisza National Museum.
Visit the Sabatini Gardens and the Catedral de la Almudena.
Explore the Alcazar of Toledo and El Greco Museum.
Explore the park and visit the Prado Museum.
Enjoy a traditional Spanish flamenco show and sample tapas at a local restaurant.
Explore the botanical gardens and head to the La Latina neighborhood for food and drinks.
Visit the University of Salamanca and the Catedral Vieja.
Explore the surrounding area and visit the El Rastro flea market.
Join a food tour to explore the city's culinary offerings.
If you have more time, consider taking a day trip to Segovia to see the Roman aqueduct or visit the Bernabeu Stadium to take a tour of the Real Madrid C.F. stadium. If you have less time, consider combining days 2 and 5 to visit both art museums in one day or skipping the day trip to Salamanca.