Most of the attractions in Rome are within walking distance of each other so consider bringing comfortable walking shoes. Public transportation is also available with buses, trams and metros. A single journey costs €1.50 and a day pass costs €7. Make sure to validate your tickets to avoid fines.
If you have more time, consider taking a day trip to nearby towns like Pompeii or Florence. If you have less time, prioritize the Colosseum, Vatican Museums and Pantheon. Be aware of pickpockets in crowded areas and keep your belongings close to you. Don't forget to taste some gelato and pizza during your stay!