Walk through the historic shopping arcade and admire the grand opera house façade; consider an optional guided tour of La Scala Museum (open 9:00am-5:30pm).
Book tickets in advance to see Leonardo da Vinci’s The Last Supper fresco; the guided tour lasts about 15 minutes plus museum visit. Open 8:15am-7:00pm.
Take a public ferry or private boat around the lake to visit Bellagio and Varenna, famous picturesque towns with villas and gardens. Boat service typically runs 9:00am to 6:00pm.