Italy has excellent public transport with trains, buses, and metros, and taxis are readily available. Buses and metros are the cheapest options, but the easiest way to travel around Italy is by renting a car. However, it's essential to have a map, GPS and driving license while driving in Italy. The approximate travel time between these destinations is 15-30 minutes.
If you have more time, you can also explore other local attractions such as the Roman Forum and Palatine Hill or hop-on-hop-off buses. Also, be sure to wear comfortable shoes and clothing, as the itinerary involves lots of walking. If you have less time, you can choose either the Colosseum or Vatican museums.
The primary airport in Rome is the Fiumicino Airport (FCO), located about 16 miles from the city center of Rome. Another airport near Rome is the Ciampino Airport (CIA), located about 12 miles away from the city center. Both airports are well connected with the city through taxis, buses, and trains that run frequently.